From “The Encomederos of New Spain 1521 – 1555” by Robert Himmerich y Valencia p. 195:

Dona Isabel married first Aztec Emperor Cuauhtemoc, first conqueror Alonso Grado [died ca. 1527], poblador Pedro Gallego [died ca. 1531], and Juan Cano. Her inheritance her father included Chapulguacan – also called Macuilsuchil –[125 miles south of Mexico City; nine estancias and 54 lesser settlements], Ocoyoaca [recovered ca. 1540 from Antonio Villagomez, 20 miles southwest of Mexico City],
Tepecxoyuca [28 miles southwest of Mexico City], Cuapanoaya [ near Tepexoyuca, southweest of Mexico City], and Tacuba [50 or more estancias and pueblos in 1593). Tributes were granted in perputity to her heirs. Dona Isabel died ca 1551. Chapulguacan went to Don Pedro Cano, her son Juan Cano. Tacuba was dived between Juan Cano, his sons Pedro and Gonzalo, and dona Isabel’s son, don Juan de Andrade [Gallego] Moctezuma by Pedro Gallego. The grants southwest of Mexico Citey were dibided in like manner. Dona Isabel also had a daughter by Cotes, named dona Lenor Cortes Moctezuma who married the metchant Juan de Tolosa.

[Gehard, 184, 186, 247ff. and 271; Schloes and Adams, 29; Liss, 130, Diaz and Castillo, II, 437.]

Juan Cano p, 135:

Cano did not become an encomendero until his 1536 marriage to Isabel Moctezuma [he was her fourth husband]. He was assigned Macuilsuchil [85 miles north of Mexico City, 120 dependecies in 1537]. The pair had four sons and two daughters. Cano renounced his claims to the tribute from this ecomenderia in favor of their son Pedro, in 1560, ten years after dona Isabel died. Pedro was succeed by his daughters in 1570s. Tributes were paid to the Cano family at least until 1631.

[Gerhard, 185 adn 186; Schloes and Adams , 17; Icaza, I, 31; Boyd -Bowman, I , no. 909, 32]

From “The Encomederos of New Spain 1521 – 1555” by Robert Himmerich y Valencia p. 195:

Dona Isabel married first Aztec Emperor Cuauhtemoc, first conqueror Alonso Grado [died ca. 1527], poblador Pedro Gallego [died ca. 1531], and Juan Cano. Her inheritance her father included Chapulguacan – also called Macuilsuchil –[125 miles south of Mexico City; nine estancias and 54 lesser settlements], Ocoyoaca [recovered ca. 1540 from Antonio Villagomez, 20 miles southwest of Mexico City],
Tepecxoyuca [28 miles southwest of Mexico City], Cuapanoaya [ near Tepexoyuca, southweest of Mexico City], and Tacuba [50 or more estancias and pueblos in 1593). Tributes were granted in perputity to her heirs. Dona Isabel died ca 1551. Chapulguacan went to Don Pedro Cano, her son Juan Cano. Tacuba was dived between Juan Cano, his sons Pedro and Gonzalo, and dona Isabel’s son, don Juan de Andrade [Gallego] Moctezuma by Pedro Gallego. The grants southwest of Mexico Citey were dibided in like manner. Dona Isabel also had a daughter by Cotes, named dona Lenor Cortes Moctezuma who married the metchant Juan de Tolosa.

[Gehard, 184, 186, 247ff. and 271; Schloes and Adams, 29; Liss, 130, Diaz and Castillo, II, 437.]

Juan Cano p, 135:

Cano did not become an encomendero until his 1536 marriage to Isabel Moctezuma [he was her fourth husband]. He was assigned Macuilsuchil [85 miles north of Mexico City, 120 dependecies in 1537]. The pair had four sons and two daughters. Cano renounced his claims to the tribute from this ecomenderia in favor of their son Pedro, in 1560, ten years after dona Isabel died. Pedro was succeed by his daughters in 1570s. Tributes were paid to the Cano family at least until 1631.

[Gerhard, 185 adn 186; Schloes and Adams , 17; Icaza, I, 31; Boyd -Bowman, I , no. 909, 32]

From “The Encomederos of New Spain 1521 – 1555” by Robert Himmerich y Valencia p.196:

In 1527 Cortes assigned dona Leonor, dona Isabel’s yoouger sister, the perpetual encomienda of Ecatepec [12 miles north of Mexico City; including cabeceras Coatitlan and Acalhuacan, formerly under Tlatclolco, plus 10 or 12 esstancia] as her patrimony. She married Juan Paz in the 1520s and then the poblador Cristobal de Valderrama, after Paz died. Dona Leonor succeeded Valderrama ca. 1537 and transferred the tribute to her daughter, dona Leonor de Valderrama y Moctezuma, who was married to Diego Arias de Sotelo. When Arias was exiled in 1568, the ecomienda went to their son, Don Fernando Sotelo de Moctezuma. In 1593, Fernando transferred a third of the tribute to his youger brother, don Cristobal de Sotelo Valderrama. Don Cristobal’s share was reassigned when he died in 1607, and don Fernando’s sons soldtheremaining two third shares.

{Gerhard, 266. Schloes and Adams , 27]

From “The Encomederos of New Spain 1521 – 1555” by Robert Himmerich y Valencia p.196:

In 1527 Cortes assigned dona Leonor, dona Isabel’s yoouger sister, the perpetual encomienda of Ecatepec [12 miles north of Mexico City; including cabeceras Coatitlan and Acalhuacan, formerly under Tlatclolco, plus 10 or 12 esstancia] as her patrimony. She married Juan Paz in the 1520s and then the poblador Cristobal de Valderrama, after Paz died. Dona Leonor succeeded Valderrama ca. 1537 and transferred the tribute to her daughter, dona Leonor de Valderrama y Moctezuma, who was married to Diego Arias de Sotelo. When Arias was exiled in 1568, the ecomienda went to their son, Don Fernando Sotelo de Moctezuma. In 1593, Fernando transferred a third of the tribute to his youger brother, don Cristobal de Sotelo Valderrama. Don Cristobal’s share was reassigned when he died in 1607, and don Fernando’s sons soldtheremaining two third shares.

{Gerhard, 266. Schloes and Adams , 27]